• 4Well Magnesium 610 mg jar, lid open with white capsules, beside spinach, walnuts and bananas
  • Woman resting on a pillow beside benefit labels: relaxed muscles, better sleep, stress relief, heart and bone
  • 4Well Magnesium jar with callouts for magnesium glycinate, magnesium citrate, vitamin B6 and 5-HTP
  • Bar chart comparing the bioavailability of 4Well Magnesium Advanced Formula with regular magnesium
  • Comparison table of 4Well Magnesium against an unbranded bottle on absorption, dose, origin and testing
  • Supplement Facts panel: 3 capsules give vitamin B6 10 mg, magnesium 400 mg and 5-HTP 200 mg
  • Two people in sportswear beside survey figures on relaxation, sleep quality and stress relief
  • Man holding a dumbbell in a gym beside a list of muscle and recovery benefits
  • Timeline of what to expect from magnesium after a few days, a few weeks and a few months

Magnesium Advanced Complex 610Mg with Glycinate, Citrate, Vitamin B6 for 3X Absorption & 5-HTP

Two forms of magnesium, with B6 and 5-HTP

Two forms of magnesium — glycinate and citrate — with vitamin B6 and 5-HTP, 610 mg per serving. Formulated to support emotional wellness, muscle recovery and daily balance.*

Three capsules in the evening. Thirty servings per bottle.

Magnesium Glycinate + Citrate with Vitamin B6 and 5-HTP — 610 mg per serving

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Not right for you? Email us within 60 days of delivery for a full refund on your first order of each formula, opened bottles included. No need to send it back.

3rd-Party Lab Tested
GMP-Certified Facility
Made in the USA
Mood and calm
Muscle recovery
Daily balance
Two magnesium forms
3× absorption blend
Vitamin B6 included
MINERAL
Magnesium Glycinate
Chelated to glycine and chosen for gentleness. The label lists glycinate and citrate together as 400 mg of magnesium per serving.
MINERAL
Magnesium Citrate
The second form in the blend, alongside glycinate. Both are counted in the same 400 mg of magnesium on the label.
VITAMIN B6
Pyridoxine · 10 mg
Vitamin B6 as pyridoxal 5-phosphate, the active form. Works together with magnesium in the body.*
AMINO ACID
5-HTP · 200 mg
5-hydroxytryptophan, included in the blend for emotional wellness support.* Read the warnings before use if you take medication.
  1. Take the serving indicated on the label daily, preferably in the evening with water.

Same time every evening. Consistency matters more than the exact hour.

Consumer Approved

Results from a 30-day consumer survey tracking nightly relaxation, muscle ease, and sleep quality.

98%
experienced faster sleep onset and calm nighttime physical relaxation1
93%
experienced significant relief from tight leg muscles and evening cramps2
89%
reported gentle, comfortable digestion with zero laxative side effects1

¹ Based on a 30-day consumer perception questionnaire of participants taking 2 capsules 45 minutes before bed. ² Muscle comfort survey. *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

The problem

One formula for the body and the mind.

Magnesium works in the nervous system and in muscle at the same time, which is why the same shortfall can show up as a restless evening and a slow recovery.*

This formula uses two forms rather than one. Glycinate is chelated to glycine and chosen for gentleness; citrate sits alongside it. Vitamin B6 is included because it works together with magnesium in the body, and 5-HTP because mood and sleep belong to the same picture as muscle and nerve.*

The label lists every milligram: 400 mg of magnesium, 200 mg of 5-HTP and 10 mg of B6 per three-capsule serving. Nothing sits behind the word blend.

Honest fit

Built for one pattern in particular.

This is for you if

  • Your evenings are restless and your mind is still going at bedtime
  • You train, or you are on your feet all day, and recovery is slow
  • Stress is constant rather than occasional
  • You have tried magnesium oxide and found it did not agree with you

This is not for you if

  • You are pregnant, trying to conceive, or breastfeeding
  • You are under 18
  • You take antidepressant, migraine or sedative medication — speak with your doctor first
  • You want something for the morning. This is an evening formula

Not for use during pregnancy, while trying to conceive, or while breastfeeding. Not for anyone under 18.

This formula contains 5-HTP. If you take prescription medication — in particular antidepressants — speak with your doctor before use.

Illustration

The difference an evening routine makes.

Drag the slider to compare a restless evening with a settled one.

After Before Before After

Illustration, not a customer photograph. Individual experience varies.

Magnesium Advanced Complex 610Mg with Glycinate, Citrate, Vitamin B6 for 3X Absorption & 5-HTP

The 4Well Standard

Doses you can check on the label.

Every batch is formulated to the dose stated on the label, made in a GMP-registered facility and checked against label claims before release — so what is on the label is what is in the capsule.

400 mg Magnesium from glycinate and citrate together
200 mg 5-HTP per serving
10 mg Vitamin B6 as pyridoxal 5-phosphate
30 Servings per bottle, three capsules each
4Well Magnesium Standard Formula Breakdown

What the research says

What the research says about these ingredients.

Below is what peer-reviewed research reports about the ingredients in this formula. These are findings about ingredients, not claims about this product.†

Pyridoxine

Magnesium with vitamin B6, and magnesium alone, in stressed adults

A randomized trial in 264 healthy adults with low blood magnesium compared 300 mg of magnesium plus 30 mg of vitamin B6 against 300 mg of magnesium alone over eight weeks. Both arms reduced the stress score by a similar amount — 44.9 % and 42.4 % — and the difference between them was not statistically significant.

An advantage for the combination appeared only in the subgroup that started with severe stress. Worth stating plainly: this trial does not show that adding B6 improves magnesium for everyone. This formula provides 400 mg of magnesium and 10 mg of B6 per serving — more magnesium than the trial, and less B6.

Pouteau E et al. PLoS One 2018;13(12):e0208454. PubMed 30562392→

Read the other studies — 3 more Show fewer

Magnesium Glycinate

Why magnesium and stress reinforce each other

A review in Nutrients describes the relationship between magnesium and stress as a loop rather than a one-way street: stress increases magnesium loss, and lower magnesium status in turn raises stress reactivity.

The authors note that magnesium supplementation, particularly alongside vitamin B6, has been examined as a way to interrupt that cycle. This is a review of the literature, not a trial of any product.

Pickering G et al. Nutrients 2020;12(12). PubMed 33260549→

Pyridoxine

Magnesium and vitamin B6 on mental health and quality of life

A randomized controlled trial in stressed healthy adults, using the same 300 mg magnesium and 30 mg vitamin B6 combination, looked at mental health and quality-of-life measures rather than a single stress score.

It sits alongside the trial above as the second published look at this pairing in people who are not ill, which is the population this product is for.

Noah L et al. Stress Health 2021;37(5):1000-1009. PubMed 33864354→

5-HTP

5-HTP and sleep quality in older adults

A randomized controlled trial gave 100 mg of 5-HTP daily to older adults and followed sleep quality and gut microbiota over twelve weeks. Serum serotonin rose, and certain components of sleep quality improved.

Two details matter. The improvement appeared in participants who were poor sleepers at the start, not in those already sleeping well. And the dose in the trial was 100 mg — half the 200 mg per serving on this label.

Sutanto CN et al. Clin Nutr 2024;43(3):593-602. PubMed 38309227→

† These statements have not been evaluated by the Food and Drug Administration. The studies cited above examined individual ingredients and were not conducted on this finished product. Please consult your healthcare provider before starting any supplement.

The difference

How we stand against typical alternatives.

Form of magnesium
Magnesium per serving
Full label transparency
Targeted synergists
Manufacturing standard
4Well Formula
✓ Glycinate and citrate, both chelated
✓ 400 mg, printed on the label
✓ Exact mg of each active
✓ Vitamin B6 and 5-HTP included
✓ cGMP facility in the USA
Generic Drugstore Brands
✗ Low-grade oxide
✗ Amount not stated
✗ Hidden proprietary blend
✗ Isolated single mineral
✗ Unverified source

Swipe the table sideways to see both columns

  • Magnesium Glycinate
  • Magnesium Citrate
  • Vitamin B6 (P-5-P)
  • 5-HTP
  • 610 mg per serving
  • 30 servings
  • Non-GMO
  • Third-Party Tested
  • Made in the USA

What is inside

Every milligram on the label.

  • Magnesium Glycinate

    Chelated to glycine and chosen for gentleness. The label lists glycinate and citrate together as 400 mg of magnesium per serving.

    MINERAL

  • Magnesium Citrate

    The second form in the blend, alongside glycinate. Both are counted in the same 400 mg of magnesium on the label.

    MINERAL
  • 10 mg

    Pyridoxine

    Vitamin B6 as pyridoxal 5-phosphate, the active form. Works together with magnesium in the body.*

    VITAMIN B6
  • 200 mg

    5-HTP

    5-hydroxytryptophan, included in the blend for emotional wellness support.* Read the warnings before use if you take medication.

    AMINO ACID

* These statements have not been evaluated by the Food and Drug Administration.

What the experts say

“Each three-capsule serving is 610 mg of named actives: 400 mg of magnesium from citrate and glycinate, 200 mg of 5-HTP and 10 mg of vitamin B6 as pyridoxal 5-phosphate. The panel states magnesium as one line from two forms rather than splitting them.”

— The 4Well Nutrition Team

Before you buy

Questions we get most.

What is 4Well Magnesium Advanced Complex?

An evening magnesium complex: 610 mg per serving, combining two forms of magnesium — glycinate and citrate — with vitamin B6 and 5-HTP.

Every active is printed with its own number on the supplement facts panel instead of being hidden inside a proprietary blend, so you can see exactly how much of each form you are taking. The two magnesium forms are there for different reasons, vitamin B6 is included to support magnesium's absorption and the nervous system, and 5-HTP is in the formula because this is built for the end of the day rather than the start of it.*

How do you take it?

Three capsules daily, in the evening, with water.

The evening timing is deliberate rather than arbitrary: this is a wind-down formula, not a morning one, which is why 5-HTP sits alongside the magnesium. Take all three capsules together rather than splitting them across the day — 610 mg is the full serving, so a split dose is a partial one. If supplements sit heavily on an empty stomach for you, take them with or shortly after your evening meal. Regularity matters more than the exact hour: keep to roughly the same slot each evening.

Why two forms of magnesium?

Because glycinate and citrate behave differently, and the formula uses each for what it does best.

Glycinate is a chelated form, chosen for gentleness and absorption; citrate sits alongside it in the complex. Both are named on the panel with their own numbers, and that is the point — “magnesium 610 mg” on a front label tells you almost nothing on its own, because the form is where absorption differences live. Magnesium oxide is the cheapest form on the market and the one most often used to inflate a front-of-bottle number. It is not in this formula.

Who is it for?

Healthy adults who want daily magnesium support in the evening.

It is not intended for children. It is also not the right product if you are pregnant, trying to conceive, or breastfeeding. If you take antidepressant, migraine or sedative medication, speak with your doctor before starting — that caution is about the 5-HTP in the formula, not the magnesium. And if you are looking for something to take in the morning, this is the wrong product: it is built for the wind-down end of the day.

Is it tested?

Yes — every batch is checked against its label claims before it is released.

Manufacturing happens in a GMP-registered facility in the United States, and testing is done on the finished capsule rather than only on incoming raw material. That distinction matters: it is the difference between knowing what went into the blender and knowing what ended up in the bottle you received. If you want the certificate of analysis for your specific batch, email info@4well.com with the lot number printed on your label and we will send it to you.

What is your guarantee?

Sixty days from the day your order arrives, and you do not have to send the bottle back.

If the formula is not right for you, email info@4well.com with your order number within that window and we refund you. There is no return shipping to arrange and no requirement that the bottle be unopened — a guarantee that only accepts sealed bottles would be meaningless for a supplement, because you cannot find out whether one suits you without taking it. Refunds are processed within two business days and go back to your original payment method; your bank usually posts the credit within another three to five. Cancelling a subscription and requesting a refund are separate actions.

Have questions about third-party testing, dosing, or guarantees?

Explore all 56 questions and direct clinical answers in our comprehensive FAQ Hub.

Explore FAQ Hub →

Build the routine

Pairs well with.

Chosen for where each one sits in the day, not for anything the combination is said to do.

Real Reviews, Real Results

See what our community is saying

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Loved By Customers

Real reviews, published in full.

Published exactly as written by verified 4Well customers.

  • Finally sleeping through the night without waking up groggy

    I've struggled with broken sleep and waking up at 3 a.m. with my mind racing for over a year. Standard drugstore magnesium oxide always tore my stomach up. This complex (glycinate + citrate) is completely gentle on my digestion. Within a week of taking 3 capsules an hour before bed, I started falling asleep naturally and actually waking up feeling genuinely rested.

    Elena R.Verified Buyer · July 28, 2026 Verified purchase

  • Nighttime leg cramps completely gone

    I do high-intensity interval training and evening runs, and nighttime calf cramps were waking me up constantly. My trainer recommended chelated magnesium with B6 for absorption. Two weeks in, the twitching and muscle tightness have completely stopped. Recovery feels much faster.

    Marcus T.Verified Buyer · August 4, 2026 Verified purchase

  • The addition of 5-HTP and B6 makes a noticeable difference

    Most magnesium supplements just give you one cheap form. 4Well combining bioavailable glycinate and citrate with active P-5-P and 5-HTP creates a genuine sense of evening calm. It doesn't knock you out like a sleep pill; it just allows your nervous system to wind down smoothly.

    Rachel K.Verified Buyer · August 11, 2026 Verified purchase

  • Effective relaxation, capsules are easy to take

    Three capsules per serving is standard for a full 610mg chelated dose, and they go down easily with water. Really helps calm down work anxiety before bed. Giving 4 stars only because shipping took an extra two days, but the formula itself is easily the best magnesium I have tried.

    David S.Verified Buyer · August 14, 2026 Verified purchase

  • Gentle on sensitive stomach

    I have IBS and almost every mineral supplement causes stomach upset. 4Well did their homework using bisglycinate chelate. Zero nausea, zero digestive issues even when taken on an empty stomach right before turning the lights out.

    Jessica L.Verified Buyer · August 18, 2026 Verified purchase

  • Noticeable boost in deep sleep tracker scores

    I track my sleep with an Oura ring. Over 30 days of consistent use, my deep sleep metrics increased from an average of 42 minutes to over 1 hour and 15 minutes per night. Waking heart rate in the morning is lower and more settled.

    Nathan B.Verified Buyer · August 21, 2026 Verified purchase

  • Clean formula with full label transparency

    Finding a brand that avoids hidden 'proprietary blends' and actually tells you the exact milligrams of active elemental magnesium is rare. The third-party testing and cGMP manufacturing give me complete peace of mind. On my second bottle already.

    Amanda C.Verified Buyer · August 24, 2026 Verified purchase

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    * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    Not for use during pregnancy, while trying to conceive, or while breastfeeding. Not for anyone under 18.

    This formula contains 5-HTP (5-hydroxytryptophan). If you take prescription medication — in particular antidepressants, migraine medication or sedatives — speak with your doctor before use.

    Other ingredients: hydroxypropyl methylcellulose, microcrystalline cellulose, magnesium stearate, silicon dioxide.

    Keep out of reach of children. Discontinue use and seek medical advice if you experience an adverse reaction. Do not exceed the recommended serving.